Noradrenergic cell group A6
Noradrenergic cell group A6 is a collection of neurons that produce norepinephrine and are located in the locus coeruleus of the brainstem. This group of neurons is part of the Aminergic cell groups and plays a crucial role in the central nervous system.
Anatomy[edit | edit source]
The A6 cell group is located in the posterior part of the rostral pons, in the lateral floor of the fourth ventricle. It is the principal site of norepinephrine production in the brain. The neurons in this group are small, multipolar, and densely packed.
Function[edit | edit source]
The A6 cell group is involved in a variety of physiological processes. It plays a key role in the regulation of sleep-wake cycle, attention, and memory. It also contributes to the modulation of pain and the response to stress.
Clinical significance[edit | edit source]
Alterations in the function of the A6 cell group have been implicated in several neurological and psychiatric disorders, including Parkinson's disease, Alzheimer's disease, depression, and post-traumatic stress disorder.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD