OR10W1

OR10W1 is a gene that encodes a member of the olfactory receptor family of proteins. These proteins are involved in the detection of odor molecules and are part of the G protein-coupled receptor (GPCR) superfamily. Olfactory receptors are responsible for the sense of smell and are located in the olfactory epithelium of the nasal cavity.

Function

The OR10W1 gene is part of a large family of olfactory receptors that interact with odorant molecules in the nose, initiating a neuronal response that triggers the perception of a smell. These receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals.

Structure

Olfactory receptors, including OR10W1, are characterized by their 7-transmembrane domain structure, which is a common feature of GPCRs. This structure allows them to traverse the cell membrane and interact with G proteins to transmit signals inside the cell.

Genetic Information

The OR10W1 gene is located on chromosome 11 at the q24 locus. It is one of many olfactory receptor genes clustered in this region of the genome. The gene is expressed in the olfactory epithelium, where it contributes to the diversity of odorant detection.

Clinical Significance

While specific clinical implications of the OR10W1 gene are not well-documented, variations in olfactory receptor genes can affect the sense of smell. Research into olfactory receptors can provide insights into anosmia (loss of smell) and other olfactory disorders.

See Also

• Olfactory receptor
• G protein-coupled receptor
• Chromosome 11

External Links

• OR10W1 Gene - NCBI
• OR10W1 Gene - GeneCards