One gene–one enzyme hypothesis
One gene–one enzyme hypothesis - brief summary
The one gene–one enzyme hypothesis is the idea that genes act through the production of enzymes, with each gene responsible for producing a single enzyme that in turn affects a single step in a metabolic pathway. The concept was proposed by George Beadle and Edward Tatum in an influential 1941 paper on, genetic mutations in the mold, neurospora crassa, and subsequently was dubbed the one gene–one enzyme hypothesis by their collaborator Norman Horowitz. In 2004, Horowitz reminisced that these experiments founded the science of what Beadle and Tatum called 'biochemical, genetics.' In actuality they proved to be the opening gun in what became molecular, genetics and all the developments that have followed from that. The development of the one gene–one enzyme hypothesis is often considered the.
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