Oogonia

Oogonia are the female germ cells that give rise to primary oocytes by the process of mitosis. They are found in the developing ovaries of the female fetus. Oogonia are formed during the embryonic development stage and by the time of birth, they develop into primary oocytes.

Development

Oogonia are formed from primordial germ cells (PGCs) that migrate from the yolk sac to the gonadal ridge in the embryo. This process is known as gonadal differentiation. The PGCs multiply by mitosis and become oogonia.

During the fetal period, the oogonia begin the first meiotic division and become primary oocytes. This process is known as oogenesis. The primary oocytes remain in a state of meiotic arrest until puberty. At puberty, each menstrual cycle allows for the completion of one meiotic division of one primary oocyte, producing a secondary oocyte.

Function

The main function of oogonia is to produce primary oocytes through the process of mitosis. They are crucial for the formation of ova or eggs in the female body.

Clinical significance

Abnormalities in the formation or development of oogonia can lead to a number of medical conditions. These include premature ovarian failure, Turner syndrome, and certain forms of infertility.

See also

• Oogenesis
• Ovarian follicle
• Oocyte

References

Oogonia Resources
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