Zygote

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Zygote

A zygote is the initial cell formed when two gametes (egg and sperm) are joined by means of sexual reproduction. In multicellular organisms, it is the earliest developmental stage of the embryo. The zygote's genome is a combination of the DNA in each gamete, and contains all of the genetic information necessary to form a new individual.

Formation[edit | edit source]

The formation of a zygote occurs through the process of fertilization, where the sperm cell from the male merges with the ovum (egg cell) from the female. This process typically occurs in the fallopian tubes in humans and other mammals. The resulting zygote is a single diploid cell, meaning it contains two sets of chromosomes, one from each parent.

Development[edit | edit source]

After fertilization, the zygote undergoes a series of rapid cell divisions known as cleavage. These divisions lead to the formation of a multicellular structure called a blastocyst in mammals, which eventually implants into the uterus to continue development. The zygote stage is followed by the embryo stage, and later the fetus stage.

Genetic Composition[edit | edit source]

The zygote's genetic material is a unique combination of the parents' DNA. This genetic recombination is crucial for genetic diversity within a species. The zygote contains alleles from both parents, which will determine the phenotype and genotype of the offspring.

Significance in Research[edit | edit source]

Zygotes are of significant interest in the fields of genetics, developmental biology, and reproductive medicine. They are used in in vitro fertilization (IVF) procedures and are studied to understand the early stages of human development and the causes of certain genetic disorders.

Related Concepts[edit | edit source]

See Also[edit | edit source]



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Contributors: Prab R. Tumpati, MD