Optic groove

Optic Groove is a significant structure in the embryonic development of the eye. It is also known as the optic sulcus or optic fissure. The optic groove forms in the optic vesicle, which is an outpouching of the diencephalon during the early stages of embryogenesis.

Formation

The optic groove forms during the third week of human embryonic development. It begins as a shallow depression in the optic vesicle, which deepens to form a groove. This groove eventually closes to form the optic cup, with the optic groove forming the fissure at the bottom of the cup.

Function

The optic groove plays a crucial role in the development of the eye. It allows for the passage of the hyaloid artery, which provides nutrients to the developing lens and retina. The groove also forms the future site of the retinal pigment epithelium, which is essential for the function of the retina.

Clinical Significance

Failure of the optic groove to close properly can lead to coloboma, a congenital eye defect. This condition can affect various parts of the eye, including the iris, retina, and optic nerve, and can lead to vision loss.

See Also

• Optic vesicle
• Optic cup
• Coloboma
• Eye development