Oxiconazole

From WikiMD's Wellness Encyclopedia

Oxiconazole is an antifungal medication used to treat skin infections such as athlete's foot, jock itch, and ringworm. It is a type of azole antifungal that works by preventing the growth of fungus.

Medical uses[edit | edit source]

Oxiconazole is used to treat skin infections such as athlete's foot, jock itch, and ringworm. It may also be used to treat a skin condition known as pityriasis, a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs.

Side effects[edit | edit source]

Common side effects of oxiconazole include burning, stinging, swelling, irritation, redness, pimple-like bumps, tenderness, or flaking of the treated skin may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Pharmacology[edit | edit source]

Oxiconazole is a broad-spectrum imidazole derivative whose antifungal activity is derived primarily from the inhibition of ergosterol biosynthesis, which is critical for cellular membrane integrity. It has a high degree of lipophilicity, which leads to high concentrations in skin and nails.

History[edit | edit source]

Oxiconazole was first approved for medical use in the United States in 1987. It is available as a cream under the brand names Oxistat in the United States and Canada, and Oxizole in India.

See also[edit | edit source]

Oxiconazole Resources
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Contributors: Prab R. Tumpati, MD