Oxiconazole

Oxiconazole is an antifungal medication used to treat skin infections such as athlete's foot, jock itch, and ringworm. It is a type of azole antifungal that works by preventing the growth of fungus.

Medical uses

Oxiconazole is used to treat skin infections such as athlete's foot, jock itch, and ringworm. It may also be used to treat a skin condition known as pityriasis, a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs.

Side effects

Common side effects of oxiconazole include burning, stinging, swelling, irritation, redness, pimple-like bumps, tenderness, or flaking of the treated skin may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Pharmacology

Oxiconazole is a broad-spectrum imidazole derivative whose antifungal activity is derived primarily from the inhibition of ergosterol biosynthesis, which is critical for cellular membrane integrity. It has a high degree of lipophilicity, which leads to high concentrations in skin and nails.

History

Oxiconazole was first approved for medical use in the United States in 1987. It is available as a cream under the brand names Oxistat in the United States and Canada, and Oxizole in India.

See also

• List of antifungal medications
• Imidazole

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  Oxiconazol
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  Oxiconazole synthesis