P200
Overview of the P200 component in event-related potentials
Overview[edit | edit source]
The P200, also known as P2, is a component of the event-related potential (ERP) that is observed in the electroencephalogram (EEG) as a positive deflection in voltage occurring approximately 200 milliseconds after the onset of a stimulus. It is typically elicited in response to auditory, visual, and somatosensory stimuli and is considered to reflect processes related to attention and the early stages of sensory processing.
Characteristics[edit | edit source]
The P200 component is characterized by its latency, amplitude, and scalp distribution. It generally appears as a broad positive wave peaking around 200 milliseconds post-stimulus. The amplitude of the P200 can vary depending on the type of stimulus and the attentional state of the individual. It is often larger for stimuli that are attended to or are of particular significance to the individual.
Functional Significance[edit | edit source]
The P200 is thought to be involved in the early stages of sensory processing and attentional mechanisms. It is associated with the detection of stimulus features and the allocation of attentional resources. The P200 is often studied in the context of cognitive neuroscience to understand how the brain processes sensory information and how attention modulates these processes.
Research Applications[edit | edit source]
The P200 component is widely used in research to investigate various cognitive processes. It has been studied in relation to auditory processing, visual perception, and somatosensory processing. Researchers often examine the P200 to understand how different factors, such as attention, expectation, and stimulus salience, influence sensory processing.
Clinical Relevance[edit | edit source]
Alterations in the P200 component have been observed in various clinical populations. For example, changes in P200 amplitude and latency have been reported in individuals with schizophrenia, attention deficit hyperactivity disorder (ADHD), and anxiety disorders. These findings suggest that the P200 may serve as a useful biomarker for certain neuropsychiatric conditions.
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Contributors: Prab R. Tumpati, MD
