PRKRIR

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Ideogram house mouse chromosome 7

PRKRIR

PRKRIR is a gene that encodes for a protein known as protein kinase interferon-inducible double-stranded RNA-dependent activator. This protein plays a crucial role in various cellular processes, particularly in the immune response to viral infections.

Function

The PRKRIR protein is involved in the activation of the interferon response pathway, which is essential for the body's defense against viral pathogens. It functions as a double-stranded RNA-dependent protein kinase, phosphorylating target proteins to regulate gene expression and cellular signaling.

Clinical Significance

Mutations in the PRKRIR gene have been associated with certain autoimmune disorders and susceptibility to viral infections. Dysregulation of PRKRIR expression can impact the immune response and contribute to disease pathogenesis.

Research

Research on PRKRIR continues to uncover its role in innate immunity and antiviral defense mechanisms. Studies are ongoing to elucidate the molecular mechanisms underlying PRKRIR function and its potential as a therapeutic target for immune-related disorders.

See Also

• Protein Kinase
• Interferon Response Pathway