PUVA keratosis

PUVA keratosis is a type of skin disorder that is caused by long-term treatment with PUVA (psoralen and ultraviolet A radiation). This condition is characterized by the development of rough, scaly patches on the skin, which are often brown or red in color.

Causes

PUVA keratosis is caused by long-term treatment with PUVA. PUVA is a type of phototherapy that is used to treat various skin conditions, including psoriasis and vitiligo. The treatment involves taking a drug called psoralen, which makes the skin more sensitive to light, and then exposing the skin to ultraviolet A (UVA) radiation.

Symptoms

The main symptom of PUVA keratosis is the development of rough, scaly patches on the skin. These patches are often brown or red in color, and they may be itchy or painful. The patches usually appear on areas of the skin that have been exposed to UVA radiation, such as the hands, arms, legs, and face.

Diagnosis

PUVA keratosis is usually diagnosed based on the patient's medical history and a physical examination of the skin. The doctor may also perform a skin biopsy to confirm the diagnosis. This involves removing a small sample of skin and examining it under a microscope.

Treatment

The treatment for PUVA keratosis depends on the severity of the condition. In mild cases, the doctor may recommend using moisturizers and sunscreens to protect the skin. In more severe cases, the doctor may prescribe topical creams or ointments, such as retinoids or corticosteroids, to reduce inflammation and promote healing. In some cases, the doctor may recommend stopping PUVA treatment.

Prevention

The best way to prevent PUVA keratosis is to limit the amount of UVA radiation that the skin is exposed to. This can be achieved by wearing protective clothing and using a high-factor sunscreen when outside. It is also important to follow the doctor's instructions when undergoing PUVA treatment.

See also

• Phototherapy
• Psoriasis
• Vitiligo
• Skin biopsy
• Retinoids
• Corticosteroids

PUVA keratosis Resources
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