Palmar crease

A palmar crease is a line that appears on the palm of the hand. These creases are formed during the development of the fetus and are present at birth. The pattern and number of palmar creases can vary among individuals and can sometimes be associated with certain medical conditions.
Types of Palmar Creases[edit]
There are typically three main palmar creases on a human hand:
- The distal transverse palmar crease, also known as the "head line," runs across the upper part of the palm.
- The proximal transverse palmar crease, also known as the "heart line," runs below the distal crease.
- The radial longitudinal crease, also known as the "life line," curves around the base of the thumb.
Single Transverse Palmar Crease[edit]
A single transverse palmar crease, commonly referred to as a "simian line," is a single line that runs across the palm, merging the distal and proximal transverse creases into one. This feature is present in approximately 1% of the general population.
Medical Significance[edit]
The presence of a single transverse palmar crease can be a normal variant, but it is also associated with certain genetic disorders and syndromes. For example, it is more commonly observed in individuals with Down syndrome, Fetal alcohol syndrome, and other chromosomal abnormalities.
Development[edit]
Palmar creases develop during the 12th week of gestation as the fetus moves its hands. The creases are formed by the flexion of the hand and are influenced by genetic and environmental factors. Once formed, the pattern of palmar creases remains unchanged throughout a person's life.
Related Pages[edit]
Sponsored Health Resource

W8MD Weight Loss, Sleep & MedSpa
Looking for physician-supervised weight loss, semaglutide, tirzepatide, or GLP-1 receptor agonist options? W8MD helps eligible patients in New York City, Brooklyn, New Jersey, Connecticut, Pennsylvania, Delaware, and greater Philadelphia with medical weight loss, sleep medicine, and long-term maintenance support.
GLP-1 specials: Affordable GLP-1 injections NYC and Philadelphia starting from $29.99/week and up for semaglutide with insurance accepted for qualifying visits, and $45/week and up for tirzepatide with insurance accepted for qualifying visits. Self-pay options start from $59.99/week and up for semaglutide and $69.99/week and up for tirzepatide.
Medical weight loss NYC | Affordable GLP-1 injections NYC | Budget GLP-1 weight loss shots Philadelphia | New Jersey medical weight loss | NYC medical weight loss | Philadelphia medical weight loss | Sleep clinic NYC | W8MD's Philadelphia GLP-1 doctor | Weight loss prescriptions NYC
Book a W8MD appointment · View GLP-1 specials
Paid promotional message. Eligibility, pricing, insurance coverage, medication availability, and results vary. Medical evaluation required.
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian