Palpable purpura

Palpable purpura is a type of purpura, a condition characterized by the appearance of red or purple discolorations on the skin. Unlike other forms of purpura, palpable purpura is characterized by its ability to be felt (palpated) due to inflammation and damage to the blood vessels (vasculitis).

Definition

Palpable purpura is a subtype of purpura that is characterized by its palpability, meaning it can be felt as a raised area on the skin. This is due to the inflammation and damage to the blood vessels, which causes them to leak blood into the surrounding tissue, leading to the characteristic discoloration.

Causes

Palpable purpura is most commonly caused by a type of vasculitis known as leukocytoclastic vasculitis. This condition involves the inflammation and damage of small blood vessels. Other causes can include certain medications, infections, and autoimmune diseases such as rheumatoid arthritis and lupus.

Symptoms

The primary symptom of palpable purpura is the appearance of red or purple spots on the skin that can be felt as raised areas. These spots are typically located on the legs, but can appear anywhere on the body. Other symptoms can include fever, joint pain, and general malaise.

Diagnosis

Diagnosis of palpable purpura typically involves a physical examination and a review of the patient's medical history. A skin biopsy may also be performed to confirm the diagnosis and rule out other potential causes.

Treatment

Treatment for palpable purpura primarily involves addressing the underlying cause. This can include discontinuing a medication that may be causing the condition, treating an infection, or managing an autoimmune disease. In some cases, anti-inflammatory medications may be used to reduce inflammation and alleviate symptoms.

See also

• Purpura
• Vasculitis
• Leukocytoclastic vasculitis
• Rheumatoid arthritis
• Lupus