Pamoic acid

A chemical compound used in pharmaceuticals

Overview

Structural formula of pamoic acid

Pamoic acid, also known as embonic acid, is a chemical compound that is commonly used in the pharmaceutical industry. It is often utilized as a counterion to form salts with various drugs, enhancing their solubility and stability. Pamoic acid is a dicarboxylic acid, which means it contains two carboxyl functional groups.

Chemical Properties

Pamoic acid is characterized by its two carboxylic acid groups, which contribute to its acidic properties. The chemical formula of pamoic acid is C₂₃H₁₆O₆. It is a yellow crystalline powder that is sparingly soluble in water but more soluble in organic solvents.

Pharmaceutical Applications

In the pharmaceutical industry, pamoic acid is used to form pamoate salts with various active pharmaceutical ingredients. These salts are often used in the formulation of medications to improve their pharmacokinetic properties. For example, pamoate salts can enhance the stability of a drug, prolong its release in the body, or improve its taste.

Mechanism of Action

Pamoic acid itself does not have a direct therapeutic effect. Instead, its role is to modify the properties of the drug it is combined with. By forming a salt with a drug, pamoic acid can alter the drug's solubility, absorption, and distribution in the body.

Safety and Toxicity

Pamoic acid is generally considered safe when used in pharmaceutical formulations. However, as with any compound, the safety profile depends on the specific drug it is combined with and the dosage form. It is important for pharmaceutical manufacturers to conduct thorough testing to ensure the safety and efficacy of pamoate salt formulations.

Related pages

• Pharmaceutical formulation
• Salt (chemistry)
• Drug solubility