Cholecystokinin

From WikiMD.com - Food, Medicine & Wellness Encyclopedia

(Redirected from Pancreozymin)

Cholecystokinin (CCK)[edit | edit source]

The molecular structure of Cholecystokinin (CCK).

Cholecystokinin (CCK) is a multifunctional peptide hormone extensively involved in the gastrointestinal and nervous systems' regulatory mechanisms. Secreted primarily by the duodenal mucosa, CCK plays a pivotal role in facilitating digestion through the regulation of gallbladder emptying and pancreatic enzyme secretion. Remarkably, its presence has also been detected in the brain, indicating a broader physiological relevance.

Overview[edit | edit source]

Cholecystokinin is synthesized and secreted by I-cells in the mucosal lining of the duodenum and jejunum, the upper segments of the small intestine. Its release is stimulated by the presence of fats and proteins in the small intestine, signaling the digestive system to begin its enzymatic and mechanical processes of food digestion.

Biological Functions[edit | edit source]

CCK's biological roles can be categorized based on its sites of action: the digestive system and the central nervous system.

Digestive System[edit | edit source]

In the digestive system, CCK is instrumental in:

  • Stimulating the gallbladder to contract and release stored bile, aiding in the emulsification and absorption of dietary fats.
  • Inducing the secretion of enzyme-rich pancreatic juice from the pancreas, critical for breaking down proteins, fats, and carbohydrates.
  • Modulating gastric motility and delaying gastric emptying to optimize nutrient digestion and absorption.
  • Enhancing the sensation of satiety and fullness, contributing to the regulation of food intake.

Central Nervous System[edit | edit source]

Within the brain, CCK is implicated in various functions, including:

  • Regulating appetite and satiety through its action in the hypothalamus.
  • Modulating anxiety, pain perception, and memory.

Clinical Significance[edit | edit source]

Understanding CCK's mechanisms has significant clinical implications, particularly in treating digestive disorders and conditions related to appetite and satiety. It has been studied in the context of obesity, gallbladder diseases, and pancreatic disorders.

Research and Future Directions[edit | edit source]

Ongoing research into CCK aims to further elucidate its roles in health and disease, with potential therapeutic applications in managing eating disorders, anxiety, and chronic pain conditions.

External Links[edit | edit source]

References[edit | edit source]

  • "The role of Cholecystokinin in digestion and satiety." Journal of Gastroenterology and Hepatology. Accessed MM/DD/YYYY.
  • "Cholecystokinin and Anxiety: From Neuron to Behavior." Studies in Neuroscience. Accessed MM/DD/YYYY.
WHO Rod.svg
This article is a medical stub. You can help WikiMD by expanding it!
PubMed
Wikipedia


Stub icon
   This article is a medical stub. You can help WikiMD by expanding it!
WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Transform your life with W8MD's budget GLP1 injections from $125 and up biweekly

W8mdlogo.png
W8MD weight loss doctors team

W8MD offers a medical weight loss program NYC and a clinic to lose weight in Philadelphia. Our W8MD's physician supervised medical weight loss centers in NYC provides expert medical guidance, and offers telemedicine options for convenience.

Why choose W8MD?

Book Your Appointment

Start your NYC weight loss journey today at our NYC medical weight loss, and Philadelphia and visit Philadelphia medical weight loss Call (718)946-5500 for NY and 215 676 2334 for PA

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's NYC physician weight loss.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available. Call 718 946 5500.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Contributors: Kondreddy Naveen