Panomifene
| Panomifene | |
|---|---|
| |
| INN | |
| Drug class | |
| Routes of administration | |
| Pregnancy category | |
| Bioavailability | |
| Metabolism | |
| Elimination half-life | |
| Excretion | |
| Legal status | |
| CAS Number | 77599-17-8 |
| PubChem | 3033654 |
| DrugBank | |
| ChemSpider | 2298282 |
| KEGG | |
Panomifene (INN) (former developmental code names GYKI-13504, EGIS-5650) is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group related to tamoxifen that was under development as an antineoplastic agent by Egis Pharmaceuticals and IVAX Drug Research Institute in the 1990s for the treatment of breast cancer but was not marketed.[1][2][3][4][5][6] It reached phase II clinical trials before development was terminated.[2] The drug was described in 1981.[1]
References[edit | edit source]
- ↑ 1.0 1.1 {{{last}}}, J. Elks, The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. online version, Springer, ISBN 978-1-4757-2085-3, Pages: 930–,
- ↑ 2.0 2.1 http://adisinsight.springer.com/drugs/800002425
- ↑ , Estrogens and Antiestrogens I: Physiology and Mechanisms of Action of Estrogens and Antiestrogens. online version, Springer Science & Business Media, ISBN 978-3-642-58616-3, Pages: 60–,
- ↑ , Estrogens and Antiestrogens II: Pharmacology and Clinical Application of Estrogens and Antiestrogen. online version, Springer Science & Business Media, ISBN 978-3-642-60107-1, Pages: 292–,
- ↑ , Ruthenium in Catalysis. online version, Springer, ISBN 978-3-319-08482-4, Pages: 385–,
- ↑ , Antiestrogens, antiandrogens, Acta Physiol Hung, 1996, Vol. 84(Issue: 4), pp. 405–6, PMID: 9328614,
External links[edit | edit source]
| Panomifene Resources | |
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