Panomifene
Panomifene[edit | edit source]
Panomifene is a nonsteroidal selective estrogen receptor modulator (SERM) that has been studied for its potential use in the treatment of breast cancer. It is structurally related to other SERMs such as tamoxifen and toremifene.
Mechanism of Action[edit | edit source]
Panomifene acts by binding to estrogen receptors in target tissues. As a SERM, it exhibits both estrogenic and antiestrogenic effects depending on the tissue type. In breast tissue, panomifene acts primarily as an antiestrogen, blocking the proliferative action of estrogen on breast cancer cells. This makes it potentially useful in the treatment and prevention of estrogen receptor-positive breast cancer.
Pharmacokinetics[edit | edit source]
The pharmacokinetic profile of panomifene includes its absorption, distribution, metabolism, and excretion. Like other SERMs, panomifene is metabolized in the liver and excreted primarily in the feces. The specific metabolic pathways and half-life of panomifene are subjects of ongoing research.
Clinical Applications[edit | edit source]
Panomifene has been investigated in clinical trials for its efficacy in treating breast cancer. Its role as a therapeutic agent is based on its ability to inhibit the growth of estrogen-dependent tumors. However, as of the latest updates, panomifene has not been approved for clinical use and remains an investigational drug.
Side Effects[edit | edit source]
The side effect profile of panomifene is similar to that of other SERMs. Common side effects may include hot flashes, nausea, and an increased risk of thromboembolic events. Long-term safety and tolerability are important considerations in the development of panomifene as a therapeutic agent.
Related Pages[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
