Para-Methoxyethylamphetamine

Para-Methoxyethylamphetamine (PMEA) is a psychoactive drug and research chemical of the phenethylamine and amphetamine classes. It is known for its entactogenic, psychedelic, and stimulant effects.

Chemistry

PMEA is a substituted amphetamine, specifically a derivative of methamphetamine. It is structurally related to para-methoxyamphetamine (PMA), para-methoxymethamphetamine (PMMA), and other designer drugs.

Pharmacology

The pharmacology of PMEA is not well studied. However, it is believed to act as a serotonin-norepinephrine-dopamine releasing agent (SNDRA) and possibly as a monoamine oxidase inhibitor (MAOI). This can lead to increased levels of these neurotransmitters in the brain, producing effects such as euphoria, increased sociability, and increased energy.

Effects

The effects of PMEA can vary greatly depending on the dose, individual physiology, and method of administration. Common effects include feelings of euphoria, increased energy, enhanced empathy and sociability, and altered perception. However, negative side effects can include anxiety, paranoia, insomnia, and potentially dangerous increases in heart rate and blood pressure.

Legal Status

The legal status of PMEA varies by country. In many places, it is a controlled substance due to its potential for abuse and its similarity to other controlled substances.

See Also

• Substituted amphetamine
• Designer drug
• Psychoactive drug