Paraolfactory area

From WikiMD's Wellness Encyclopedia

Paraolfactory Area[edit | edit source]

The Paraolfactory Area (also known as the subcallosal area, Brodmann area 25, or subgenual area) is a region located in the brain. It is part of the cerebral cortex, specifically within the cingulate cortex. This area is involved in various cognitive and emotional processes.

File:Brodmann area 25.png
Brodmann area 25, also known as the paraolfactory area.

Structure[edit | edit source]

The paraolfactory area is situated in the medial part of the brain, below the corpus callosum. It is bordered by the paraterminal gyrus anteriorly and the subcallosal gyrus posteriorly. The area is divided into two parts: the anterior and posterior paraolfactory areas.

Function[edit | edit source]

The paraolfactory area plays a crucial role in emotional regulation, particularly in relation to depression and anxiety. It is also involved in the processing of reward and punishment, and in the regulation of autonomic functions.

Clinical significance[edit | edit source]

Due to its role in emotional regulation, abnormalities in the paraolfactory area have been associated with several psychiatric disorders, including major depressive disorder, bipolar disorder, and anxiety disorders. In particular, hyperactivity in this area has been linked to treatment-resistant depression.

See also[edit | edit source]

References[edit | edit source]


External links[edit | edit source]


WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD