Paraolfactory area
Paraolfactory Area[edit | edit source]
The Paraolfactory Area (also known as the subcallosal area, Brodmann area 25, or subgenual area) is a region located in the brain. It is part of the cerebral cortex, specifically within the cingulate cortex. This area is involved in various cognitive and emotional processes.
Structure[edit | edit source]
The paraolfactory area is situated in the medial part of the brain, below the corpus callosum. It is bordered by the paraterminal gyrus anteriorly and the subcallosal gyrus posteriorly. The area is divided into two parts: the anterior and posterior paraolfactory areas.
Function[edit | edit source]
The paraolfactory area plays a crucial role in emotional regulation, particularly in relation to depression and anxiety. It is also involved in the processing of reward and punishment, and in the regulation of autonomic functions.
Clinical significance[edit | edit source]
Due to its role in emotional regulation, abnormalities in the paraolfactory area have been associated with several psychiatric disorders, including major depressive disorder, bipolar disorder, and anxiety disorders. In particular, hyperactivity in this area has been linked to treatment-resistant depression.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
- Paraolfactory area at BrainInfo
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Contributors: Prab R. Tumpati, MD
