Percutaneous umbilical blood sampling
Percutaneous umbilical blood sampling
Percutaneous umbilical blood sampling (PUBS), also known as cordocentesis, is a diagnostic medical procedure used in prenatal diagnosis to obtain a small sample of the fetal blood from the umbilical cord. This procedure is typically performed to detect fetal abnormalities, manage intrauterine infections, or assess and treat fetal anemias.
Indications[edit | edit source]
Percutaneous umbilical blood sampling is indicated in various scenarios including:
- Diagnosis of genetic disorders and chromosomal abnormalities
- Assessment of fetal infections
- Evaluation of fetal anemia
- Determination of fetal blood type and Rh factor
- Assessment of fetal platelets count in cases of maternal immune thrombocytopenic purpura
Procedure[edit | edit source]
During the procedure, a skilled practitioner uses ultrasound guidance to locate the umbilical cord and then inserts a thin needle through the mother's abdominal wall and uterus into the umbilical vein. The blood sample obtained is then analyzed for various conditions or abnormalities.
Risks[edit | edit source]
Percutaneous umbilical blood sampling carries risks such as:
Alternatives[edit | edit source]
Alternative procedures to PUBS include:
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
