Perichondrium
Perichondrium
The Perichondrium is a layer of dense irregular connective tissue which surrounds the cartilage of developing bone. It is involved in the growth and repair of cartilage.
Structure[edit | edit source]
The perichondrium consists of two layers: an outer fibrous layer and an inner chondrogenic layer. The fibrous layer contains fibroblasts, which produce collagen, and the chondrogenic layer produces chondroblasts, which form cartilage.
Function[edit | edit source]
The perichondrium serves several functions: it acts as a source of new cartilage cells, it is involved in the growth and repair of cartilage, and it provides nutrients to the cartilage.
Clinical significance[edit | edit source]
Damage to the perichondrium can lead to a variety of medical conditions, including osteoarthritis and rheumatoid arthritis. In addition, the perichondrium plays a key role in the surgical procedure known as autologous chondrocyte implantation.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
- Perichondrium at the US National Library of Medicine Medical Subject Headings (MeSH)
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Contributors: Prab R. Tumpati, MD
