Perivascular

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Perivascular refers to the area surrounding a blood vessel. This term is often used in the context of pathology, anatomy, and physiology to describe the location of structures or processes in relation to the blood vessels.

Anatomy[edit | edit source]

In the context of anatomy, perivascular spaces, also known as Virchow-Robin spaces, are spaces in the brain that surround the blood vessels as they penetrate into the brain. These spaces are filled with cerebrospinal fluid (CSF) and are involved in the exchange of substances between the CSF and the brain.

Pathology[edit | edit source]

In pathology, perivascular inflammation, also known as perivasculitis, refers to the inflammation of the area surrounding a blood vessel. This can occur in various diseases, such as vasculitis, rheumatoid arthritis, and lupus erythematosus. Perivascular inflammation can lead to damage to the blood vessel and surrounding tissues, resulting in various symptoms depending on the location and extent of the inflammation.

Physiology[edit | edit source]

In physiology, perivascular cells, also known as pericytes, are cells that wrap around the endothelial cells of capillaries and venules throughout the body. They are involved in the regulation of blood flow, the permeability of the blood-brain barrier, and the clearance of cellular debris.

See also[edit | edit source]

Perivascular Resources
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Contributors: Prab R. Tumpati, MD