Phenylethylidenehydrazine

Phenylethylidenehydrazine

Phenylethylidenehydrazine is a chemical compound with the molecular formula C8H10N2. It is a derivative of hydrazine, a simple diamine, and is known for its use in the synthesis of various pharmaceuticals.

Chemistry

Phenylethylidenehydrazine is a hydrazine derivative, meaning it contains the -NHNH2 functional group. This compound is characterized by the presence of a phenyl group (C6H5-) and an ethylidene group (-CH=CH2) attached to the hydrazine moiety. The phenyl group is a common aromatic ring found in many organic compounds, while the ethylidene group is a type of alkene, a hydrocarbon with a carbon-carbon double bond.

Synthesis

The synthesis of phenylethylidenehydrazine typically involves the reaction of phenylhydrazine with acetaldehyde in the presence of an acid catalyst. This reaction proceeds via a condensation mechanism, with the elimination of a water molecule.

Applications

Phenylethylidenehydrazine has been used in the synthesis of various pharmaceuticals. For example, it is a key intermediate in the production of phenelzine, a monoamine oxidase inhibitor used in the treatment of depression.

Safety

As with many hydrazine derivatives, phenylethylidenehydrazine is potentially hazardous. It can cause skin and eye irritation, and prolonged exposure may lead to more serious health effects. Appropriate safety measures should be taken when handling this compound.

See also

• Phenylhydrazine
• Acetaldehyde
• Phenelzine

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