Pindborg tumor

Pindborg Tumor The Pindborg tumor, also known as the calcifying epithelial odontogenic tumor (CEOT), is a rare, benign odontogenic tumor. It was first described by Jens J rgen Pindborg in 1955. This tumor is characterized by its unique histological features and clinical behavior.

Clinical Presentation

Patients with a Pindborg tumor typically present with a painless, slow-growing mass in the jaw. The tumor most commonly affects the posterior mandible, but it can also occur in the maxilla. It is often associated with an impacted tooth, particularly the mandibular molars.

Histopathology

The Pindborg tumor is characterized by sheets and islands of polyhedral epithelial cells with prominent intercellular bridges. A distinctive feature is the presence of amyloid-like deposits that can calcify, forming concentric "Liesegang rings." These calcifications are a hallmark of the tumor and aid in its diagnosis.

Diagnosis

Diagnosis of a Pindborg tumor is primarily based on histological examination. Radiographically, the tumor may appear as a unilocular or multilocular radiolucency with calcifications. A biopsy is necessary to confirm the diagnosis and differentiate it from other odontogenic tumors.

Treatment

The treatment of choice for a Pindborg tumor is surgical excision. Due to its benign nature, conservative resection is often sufficient. However, recurrence can occur, so long-term follow-up is recommended.

Prognosis

The prognosis for patients with a Pindborg tumor is generally good, given its benign nature. Recurrence rates vary, but they are generally low with adequate surgical removal.

Epidemiology

Pindborg tumors are rare, accounting for less than 1% of all odontogenic tumors. They can occur at any age but are most commonly diagnosed in adults between the ages of 30 and 50. There is no significant gender predilection.

See Also

• Odontogenic tumors
• Ameloblastoma
• Odontogenic keratocyst
• Pindborg, J. J. (1955). "Calcifying epithelial odontogenic tumors." Acta Pathologica Microbiologica Scandinavica.
• Neville, B. W., Damm, D. D., Allen, C. M., & Bouquot, J. E. (2002). Oral and Maxillofacial Pathology.

NIH genetic and rare disease info

• NIH info on Pindborg tumor

Pindborg tumor is a rare disease.