Positive likelihood ratio
Positive likelihood ratio
The positive likelihood ratio (LR+) is a statistical measure used in diagnostic testing in medicine. It is the ratio of the probability of a positive test result given the presence of the disease to the probability of a positive test result given the absence of the disease.
Definition[edit | edit source]
The positive likelihood ratio is defined as:
- LR+ = Sensitivity / (1 - Specificity)
where Sensitivity is the probability of a positive test result given the presence of the disease, and Specificity is the probability of a negative test result given the absence of the disease.
Interpretation[edit | edit source]
The LR+ is interpreted as follows:
- An LR+ greater than 1 increases the probability of disease.
- An LR+ less than 1 decreases the probability of disease.
- An LR+ of 1 means the test does not change the probability of disease.
Use in medicine[edit | edit source]
In medicine, the LR+ is used to assess the value of a diagnostic test. It is particularly useful in situations where the disease prevalence is low, as it provides a measure of the increase in probability of disease given a positive test result.
See also[edit | edit source]
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