Posner–Schlossman syndrome

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Posner–Schlossman syndrome (PSS), also known as glaucomatocyclitic crisis, is a rare condition characterized by recurrent episodes of elevated intraocular pressure (IOP) and mild anterior uveitis.

Symptoms[edit | edit source]

The primary symptom of PSS is a sudden onset of unilateral, mild to moderate eye pain. Other symptoms may include blurred vision, halos around lights, and mild redness of the eye. The symptoms usually resolve within a few days to a few weeks, but can recur at any time.

Causes[edit | edit source]

The exact cause of PSS is unknown. It is thought to be an autoimmune disorder, in which the body's immune system mistakenly attacks the tissues of the eye. Some researchers believe that a viral infection may trigger the immune response.

Diagnosis[edit | edit source]

Diagnosis of PSS is based on the clinical symptoms and findings on eye examination. The key diagnostic feature is an elevated IOP in the presence of a mild anterior uveitis. Other tests may include gonioscopy, visual field testing, and optical coherence tomography.

Treatment[edit | edit source]

Treatment of PSS is aimed at reducing the IOP and controlling the inflammation. This may involve the use of topical corticosteroids and IOP-lowering medications. In some cases, surgery may be required to control the IOP.

Prognosis[edit | edit source]

The prognosis for PSS is generally good. Most people with PSS have a normal life expectancy and good vision. However, some people may develop glaucoma and require ongoing treatment to control the IOP and prevent vision loss.

See also[edit | edit source]

References[edit | edit source]

Posner–Schlossman syndrome Resources
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Contributors: Prab R. Tumpati, MD