Pridopidine
Pridopidine is a drug that is currently under investigation for its potential use in the treatment of Huntington's disease. It is a dopamine stabilizer that was originally developed by NeuroSearch, and is now being developed by Prilenia Therapeutics.
Mechanism of action[edit | edit source]
Pridopidine acts as a dopamine D2 receptor antagonist, and has a high affinity for sigma-1 receptors. The drug's mechanism of action is not fully understood, but it is believed to improve motor function and reduce motor symptoms in patients with Huntington's disease.
Clinical trials[edit | edit source]
Several clinical trials have been conducted to evaluate the safety and efficacy of pridopidine in patients with Huntington's disease. The results of these trials have been mixed, with some showing a significant improvement in motor function, while others have shown no significant difference between pridopidine and a placebo.
Side effects[edit | edit source]
The most common side effects of pridopidine include nausea, fatigue, and insomnia. In rare cases, pridopidine can cause serious side effects such as akathisia and dyskinesia.
Future developments[edit | edit source]
Research is ongoing to determine the long-term effects of pridopidine and its potential use in other neurodegenerative diseases. Prilenia Therapeutics is currently conducting a Phase III clinical trial to further evaluate the drug's efficacy and safety.
See also[edit | edit source]
| Pridopidine Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
