Primary lymphoid organs

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Primary Lymphoid Organs

The immune system is a complex network of cells, tissues, and organs that work together to defend the body against harmful invaders. Among these components, the primary lymphoid organs play a crucial role in the development and maturation of immune cells or lymphocytes. The primary lymphoid organs include the bone marrow and the thymus.

Bone Marrow[edit | edit source]

Human bone marrow

The bone marrow is a soft, spongy tissue found in the hollow interior of bones. It is the primary site of new blood cell production or hematopoiesis. It produces both red blood cells and white blood cells. The bone marrow is also where B cells, a type of white blood cell, mature and develop into plasma cells that produce antibodies.

Thymus[edit | edit source]

The thymus is a small organ located in the upper chest, behind the sternum. It is most active during the neonatal and pre-adolescent periods. In the thymus, T cells or T lymphocytes mature. T cells are critical for adaptive immunity, a system in the body that adapts to defend against specific pathogens.

Function[edit | edit source]

The primary lymphoid organs are where lymphocytes – B cells and T cells – grow, develop, and mature. B cells mature in the bone marrow, while T cells mature in the thymus. Once matured, these cells move to the secondary lymphoid organs, where they wait to encounter antigens.

See Also[edit | edit source]

References[edit | edit source]



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Contributors: Prab R. Tumpati, MD