Progeroid syndromes

From WikiMD's Wellnesspedia

Progeroid syndromes are a group of rare genetic disorders which mimic physiological aging, making affected individuals appear to be older than they are. The two most well-known types of progeroid syndromes are Hutchinson-Gilford Progeria Syndrome (HGPS) and Werner syndrome.

Overview[edit | edit source]

Progeroid syndromes are characterized by the early onset of diseases associated with old age. The term "progeroid" is derived from the Greek words "pro" (meaning "before") and "geras" (meaning "old age"). These syndromes are often considered to be segmental, as they do not affect all aspects of aging, but rather focus on certain areas.

Types of Progeroid Syndromes[edit | edit source]

There are several types of progeroid syndromes, including:

Symptoms[edit | edit source]

The symptoms of progeroid syndromes can vary greatly depending on the specific syndrome, but may include:

Causes[edit | edit source]

Progeroid syndromes are caused by mutations in specific genes. For example, HGPS is caused by a mutation in the LMNA gene, while Werner syndrome is caused by a mutation in the WRN gene.

Diagnosis[edit | edit source]

Diagnosis of progeroid syndromes is based on clinical features, genetic testing, and in some cases, biopsy of affected tissues.

Treatment[edit | edit source]

There is currently no cure for progeroid syndromes. Treatment is supportive and aims to manage symptoms and improve quality of life.

See Also[edit | edit source]

References[edit | edit source]


Progeroid syndromes Resources

Find a healthcare provider anywhere in the world quickly and easily!

Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.


Contributors: Admin, Prab R. Tumpati, MD