RPL7

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RPL7


RPL7 is a protein that in humans is encoded by the RPL7 gene. This protein is a component of the 60S ribosomal subunit and belongs to the L7P family of ribosomal proteins. It is located in the cytoplasm where it plays a critical role in protein synthesis by facilitating the assembly and function of the ribosome, which is the cellular machinery responsible for translating mRNA into protein.

The RPL7 gene is highly conserved across different species, indicating its essential role in the cell. Mutations in the RPL7 gene have been associated with various human diseases, although the specific conditions linked to this gene are still under investigation. The study of RPL7 and its function in the ribosome is crucial for understanding the mechanisms of protein synthesis and its regulation in cells.

In addition to its role in protein synthesis, RPL7 has been implicated in other cellular processes, including the response to cellular stress and the regulation of apoptosis or programmed cell death. This suggests that RPL7 may have functions beyond its traditional role in the ribosome.

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Contributors: Prab R. Tumpati, MD