RTI-171

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RTI-171 structure

RTI-171 is a psychoactive compound that belongs to the phenyltropane class of substances, which are known for their stimulant effects. This compound is part of a broader group of chemicals that have been extensively studied for their potential applications in neuroscience and pharmacology, particularly in the context of substance abuse treatment and the understanding of dopamine reuptake mechanisms.

Chemistry

RTI-171 is chemically related to other compounds in the RTI series, which were developed by researchers at the Research Triangle Institute (RTI). The molecular structure of RTI-171 features a tropane ring, a characteristic shared by natural alkaloids such as cocaine, but with modifications that significantly alter its pharmacological profile. The precise chemical name and structure of RTI-171 highlight its place within the phenyltropane family and its distinctions from both natural alkaloids and other synthetic derivatives.

Pharmacology

The pharmacological action of RTI-171 is primarily centered around its ability to inhibit the reuptake of dopamine, a key neurotransmitter involved in reward, motivation, and motor function. By blocking the dopamine transporter (DAT), RTI-171 increases dopamine levels in the synaptic cleft, leading to enhanced dopaminergic signaling. This mechanism is similar to that of other well-known stimulants, including cocaine and amphetamines, but with potentially different efficacy and side effect profiles due to structural differences.

Potential Applications

Research into RTI-171 and related compounds has been driven by the search for new treatments for drug addiction, particularly cocaine and methamphetamine addiction. The unique properties of these compounds may offer advantages over existing treatments, such as reduced abuse potential or improved efficacy in reducing drug-seeking behavior. Additionally, the study of RTI-171 contributes to a deeper understanding of the dopamine system and its role in various neurological and psychiatric disorders.

Safety and Legal Status

As with many research chemicals, the safety profile of RTI-171 is not well-established. Studies in animals and any available data from human research would provide critical insights into its potential toxicological effects. The legal status of RTI-171 varies by country, with it often falling under general controlled substance regulations that cover new psychoactive substances not specifically mentioned in legislation.

See Also

• Phenyltropane
• Dopamine transporter
• Cocaine
• Amphetamine
• Drug addiction