Rogletimide

Rogletimide structure

Rogletimide, also known as pyridoglutethimide, is a drug related in chemical structure to the sedative-hypnotic glutethimide, but instead having pharmacological activity as a selective aromatase inhibitor similar to the related drug aminoglutethimide, but with no significant sedative-hypnotic effect as Glutethimide. This makes it potentially useful in the treatment of some forms of cancer, and with less side effects than aminoglutethimide, but its lower potency caused it to be unsuccessful in clinical trials.

References

Rogletimide Resources
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