S-Equol

From WikiMD's Food, Medicine & Wellness Encyclopedia

S-Equol is a non-steroidal estrogen produced by the bacterial flora in the digestive tract. It is a metabolite of daidzein, a type of isoflavone found in soy and other plant sources. S-Equol has been the subject of scientific research due to its potential health benefits, particularly in relation to menopause symptoms, bone health, and cardiovascular health.

Production[edit | edit source]

S-Equol is produced in the gut through the conversion of daidzein by certain types of bacteria. However, not all individuals are capable of producing S-Equol, with studies suggesting that only 30-50% of adults in Western countries and 50-60% of adults in Asian countries are "equol producers".

Health Benefits[edit | edit source]

Menopause Symptoms[edit | edit source]

S-Equol has been studied for its potential to alleviate menopause symptoms. It is believed to bind to estrogen receptors, which may help to mitigate the decline in estrogen levels that occurs during menopause.

Bone Health[edit | edit source]

Research has suggested that S-Equol may have beneficial effects on bone health. It may help to prevent osteoporosis by promoting bone formation and inhibiting bone resorption.

Cardiovascular Health[edit | edit source]

S-Equol may also have positive effects on cardiovascular health. Studies have indicated that it may help to reduce LDL cholesterol levels and improve arterial stiffness, both of which are risk factors for heart disease.

Safety and Side Effects[edit | edit source]

While S-Equol is generally considered safe, some individuals may experience side effects such as gastrointestinal discomfort. As with any supplement, it is recommended to consult with a healthcare provider before starting S-Equol supplementation.

See Also[edit | edit source]

S-Equol Resources
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Contributors: Prab R. Tumpati, MD