SA Node

From WikiMD's Wellness Encyclopedia

Sinoatrial node
   Heart conduction system, with the sinoatrial node labeled at the top right.
Heart conduction system, with the sinoatrial node labeled at the top right.
Latin nodus sinuatrialis
Precursor Cardiac mesoderm
System Cardiovascular system


The sinoatrial node (SA node), also known as the sinus node, is a group of specialized cardiac muscle cells located in the right atrium of the heart. It is the primary pacemaker of the heart, responsible for initiating the electrical impulses that dictate the heart's rhythm.

Structure[edit | edit source]

The SA node is a small, ellipsoid structure situated in the upper wall of the right atrium, near the entrance of the superior vena cava. It is composed of pacemaker cells that have the unique ability to generate spontaneous electrical activity. These cells are smaller than typical cardiac muscle cells and have fewer contractile fibers.

Function[edit | edit source]

The primary function of the SA node is to generate electrical impulses that propagate throughout the heart, initiating the heartbeat. The electrical activity of the SA node is influenced by the autonomic nervous system:

The SA node sets the pace for the heart under normal conditions, typically generating impulses at a rate of 60 to 100 beats per minute in a resting adult.

Clinical Significance[edit | edit source]

Dysfunction of the SA node can lead to various cardiac arrhythmias. Common conditions include:

  • Sick sinus syndrome: A collection of heart rhythm disorders due to malfunction of the SA node, leading to bradycardia, tachycardia, or a combination of both.
  • Sinus bradycardia: A slower than normal heart rate, which can be normal in athletes but may indicate SA node dysfunction in others.
  • Sinus tachycardia: A faster than normal heart rate, which can occur due to increased sympathetic stimulation or other factors.

Also see[edit | edit source]




Cardiovascular disease A-Z

Most common cardiac diseases

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