Salvinorin A

From WikiMD's Wellness Encyclopedia

{{Infobox Chemical | Name = Salvinorin A | Image = Salvinorin A.svg | ImageFile = Salvinorin A.png | ImageSize = 200px | IUPACName = (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester | OtherNames = Divinorin A | Section1 = ! colspan=2 style="background: #f8eaba; text-align: center;" |Identifiers

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3D model (JSmol)

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| 3DMet

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  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
    {{This 'chemical compound' related article is a stub.}}
  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
    {{This 'chemical compound' related article is a stub.}}
  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
    {{This 'chemical compound' related article is a stub.}}
  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
    {{This 'chemical compound' related article is a stub.}}
  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
    {{This 'chemical compound' related article is a stub.}}
  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
    {{This 'chemical compound' related article is a stub.}}

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| ChEBI

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    }}
    {{This 'chemical compound' related article is a stub.}}
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    {{This 'chemical compound' related article is a stub.}}
  • {{{{{1}}}|Name= |ImageFile= |ImageSize= |ImageAlt= |ImageCaption= |IUPACName= |OtherNames= |Section1=Template loop detected: Template:Chembox Identifiers |Section2= |Section3= |Section4= }}
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  • {{{{{1}}}|Name= |ImageFile= |ImageSize= |ImageAlt= |ImageCaption= |IUPACName= |OtherNames= |Section1=Template loop detected: Template:Chembox Identifiers |Section2= |Section3= |Section4= }}
    {{This 'chemical compound' related article is a stub.}}

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| ChEMBL

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Chembox

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ChemSpider ID[[ChemSpiderID|]]
Properties
Molecular Formula[[Molecular formula|]]
Molar Mass[[Molar mass|]] g/mol
Appearance
Densityg/cm3
Melting Point°C
Boiling Point°C
Solubility in Water
Hazards


| DrugBank

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  • {| class="infobox" style="width: 22em; font-size: 90%;"

    |+ Salvinorin A |- ! colspan="2" style="background: #EFEFEF; text-align: center;" | Drug Information |- | Image | |- Caption Synonyms ! colspan="2" style="background: #EFEFEF; text-align: center;" | Identifiers CAS Number ATC Code PubChem DrugBank ChemSpider ID UNII KEGG ChEBI ChEMBL IUPAC Name ! colspan="2" style="background: #EFEFEF; text-align: center;" | Chemical Data C H N O Molecular Weight

    |}
  • {| class="infobox" style="width: 22em; font-size: 90%;" |+ Salvinorin A |- ! colspan="2" style="background: #EFEFEF; text-align: center;" | Drug Information |- | Image | |- Caption Synonyms ! colspan="2" style="background: #EFEFEF; text-align: center;" | Identifiers CAS Number ATC Code PubChem DrugBank ChemSpider ID UNII KEGG ChEBI ChEMBL IUPAC Name ! colspan="2" style="background: #EFEFEF; text-align: center;" | Chemical Data C H N O Molecular Weight |}
  • {| class="infobox" style="width: 22em; font-size: 90%;" |+ Salvinorin A |- ! colspan="2" style="background: #EFEFEF; text-align: center;" | Drug Information |- | Image | |- Caption Synonyms ! colspan="2" style="background: #EFEFEF; text-align: center;" | Identifiers CAS Number ATC Code PubChem DrugBank ChemSpider ID UNII KEGG ChEBI ChEMBL IUPAC Name ! colspan="2" style="background: #EFEFEF; text-align: center;" | Chemical Data C H N O Molecular Weight |}
  • {| class="infobox" style="width: 22em; font-size: 90%;" |+ Salvinorin A |- ! colspan="2" style="background: #EFEFEF; text-align: center;" | Drug Information |- | Image | |- Caption Synonyms ! colspan="2" style="background: #EFEFEF; text-align: center;" | Identifiers CAS Number ATC Code PubChem DrugBank ChemSpider ID UNII KEGG ChEBI ChEMBL IUPAC Name ! colspan="2" style="background: #EFEFEF; text-align: center;" | Chemical Data C H N O Molecular Weight |}
  • {| class="infobox" style="width: 22em; font-size: 90%;" |+ Salvinorin A |- ! colspan="2" style="background: #EFEFEF; text-align: center;" | Drug Information |- | Image | |- Caption Synonyms ! colspan="2" style="background: #EFEFEF; text-align: center;" | Identifiers CAS Number ATC Code PubChem DrugBank ChemSpider ID UNII KEGG ChEBI ChEMBL IUPAC Name ! colspan="2" style="background: #EFEFEF; text-align: center;" | Chemical Data C H N O Molecular Weight |}
  • {| class="infobox" style="width: 22em; font-size: 90%;" |+ Salvinorin A |- ! colspan="2" style="background: #EFEFEF; text-align: center;" | Drug Information |- | Image | |- Caption Synonyms ! colspan="2" style="background: #EFEFEF; text-align: center;" | Identifiers CAS Number ATC Code PubChem DrugBank ChemSpider ID UNII KEGG ChEBI ChEMBL IUPAC Name ! colspan="2" style="background: #EFEFEF; text-align: center;" | Chemical Data C H N O Molecular Weight |}

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  • Salvinorin A
    IUPAC Name: {{{IUPACName}}}
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
  • Salvinorin A
    IUPAC Name: {{{IUPACName}}}
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
  • Salvinorin A
    IUPAC Name: {{{IUPACName}}}
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
  • Salvinorin A
    IUPAC Name: {{{IUPACName}}}
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
  • Salvinorin A
    IUPAC Name: {{{IUPACName}}}
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
  • Salvinorin A
    IUPAC Name: {{{IUPACName}}}
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature

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Chembox IUPHAR Ligand

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IUPHAR ID
Chemical Formula
Molecular Weight
CAS Number[[CAS Registry Number|]]
PubChem CID[[PubChem|]]
ChemSpider ID[[ChemSpider|]]
UNII[[Unique Ingredient Identifier|]]
KEGG[[KEGG|]]
ChEBI[[ChEBI|]]
Synonyms



| KEGG

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  • {{subst:PAGENAME}}
    IUPAC Name:
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    CAS Number
    PubChem
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    SMILES
    InChI
    InChIKey
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    StdInChIKey
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    Chemical formula CHNO
    Appearance
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    Solubility
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    Autoignition Temperature
  • {{subst:PAGENAME}}
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
  • {{subst:PAGENAME}}
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
  • {{subst:PAGENAME}}
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
  • {{subst:PAGENAME}}
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
  • {{subst:PAGENAME}}
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature

|-


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PubChem CID

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  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature


    ```

    This template is designed to be used for creating a standardized information box for chemical compounds on WikiMD, similar to those found on WikiMD. It includes sections for identifiers, properties, hazards, and related compounds, with fields for various specific details such as PubChem ID, molecular formula, hazards, and more. Users can fill in the relevant information for the chemical compound they are documenting. The template also includes a stub notice encouraging users to expand the article, linking to the concept of a stub and the WikiMD project for further contributions.
  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature


    ```

    This template is designed to be used for creating a standardized information box for chemical compounds on WikiMD, similar to those found on WikiMD. It includes sections for identifiers, properties, hazards, and related compounds, with fields for various specific details such as PubChem ID, molecular formula, hazards, and more. Users can fill in the relevant information for the chemical compound they are documenting. The template also includes a stub notice encouraging users to expand the article, linking to the concept of a stub and the WikiMD project for further contributions.
  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature


    ```

    This template is designed to be used for creating a standardized information box for chemical compounds on WikiMD, similar to those found on WikiMD. It includes sections for identifiers, properties, hazards, and related compounds, with fields for various specific details such as PubChem ID, molecular formula, hazards, and more. Users can fill in the relevant information for the chemical compound they are documenting. The template also includes a stub notice encouraging users to expand the article, linking to the concept of a stub and the WikiMD project for further contributions.
  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature


    ```

    This template is designed to be used for creating a standardized information box for chemical compounds on WikiMD, similar to those found on WikiMD. It includes sections for identifiers, properties, hazards, and related compounds, with fields for various specific details such as PubChem ID, molecular formula, hazards, and more. Users can fill in the relevant information for the chemical compound they are documenting. The template also includes a stub notice encouraging users to expand the article, linking to the concept of a stub and the WikiMD project for further contributions.
  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature


    ```

    This template is designed to be used for creating a standardized information box for chemical compounds on WikiMD, similar to those found on WikiMD. It includes sections for identifiers, properties, hazards, and related compounds, with fields for various specific details such as PubChem ID, molecular formula, hazards, and more. Users can fill in the relevant information for the chemical compound they are documenting. The template also includes a stub notice encouraging users to expand the article, linking to the concept of a stub and the WikiMD project for further contributions.
  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature


    ```

    This template is designed to be used for creating a standardized information box for chemical compounds on WikiMD, similar to those found on WikiMD. It includes sections for identifiers, properties, hazards, and related compounds, with fields for various specific details such as PubChem ID, molecular formula, hazards, and more. Users can fill in the relevant information for the chemical compound they are documenting. The template also includes a stub notice encouraging users to expand the article, linking to the concept of a stub and the WikiMD project for further contributions.

|-

| RTECS number

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  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature
  • Salvinorin A
    IUPAC Name:
    Other Names:
    Identifiers
    CAS Number
    PubChem
    ChemSpider
    SMILES
    InChI
    InChIKey
    StdInChI
    StdInChIKey
    Properties
    Chemical formula CHNO
    Appearance
    Density
    Melting Point
    Boiling Point
    Solubility
    Hazards
    Main Hazards
    Flash Point
    Autoignition Temperature

|-

| UNII

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|

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|-

| colspan="2" |

|-

| colspan="2" |


|- Salvinorin A is a naturally occurring hallucinogenic compound found in the leaves of the Salvia divinorum plant. It is a potent kappa-opioid receptor agonist and is known for its intense psychoactive effects. Salvinorin A is considered one of the most potent naturally occurring hallucinogens, with effects that can be felt even in small doses.

History[edit | edit source]

Salvinorin A was first isolated and identified in 1982 by a team of researchers led by Alfredo Ortega. The compound was extracted from the leaves of the Salvia divinorum plant, which has a long history of use in traditional Mexican shamanic practices. The Mazatec people, indigenous to the Oaxaca region of Mexico, have used Salvia divinorum for centuries for its hallucinogenic properties.

Chemical Properties[edit | edit source]

Salvinorin A has a molecular formula of C23H28O8 and a molecular weight of 432.47 g/mol. It is a diterpenoid compound with a complex structure consisting of a furan ring, a lactone ring, and a naphthoquinone ring. The compound is highly lipophilic, allowing it to easily cross the blood-brain barrier and exert its psychoactive effects.

Pharmacology[edit | edit source]

Salvinorin A acts as a selective agonist of the kappa-opioid receptor, a G-protein coupled receptor found in the central and peripheral nervous systems. Activation of the kappa-opioid receptor by Salvinorin A leads to a cascade of intracellular events, ultimately resulting in altered neuronal activity and the characteristic hallucinogenic effects.

Effects[edit | edit source]

The effects of Salvinorin A are rapid and intense, with the onset of hallucinations occurring within seconds to minutes after ingestion or inhalation. Users typically experience vivid visual distortions, alterations in perception of time and space, and a sense of detachment from reality. The duration of the effects is relatively short, typically lasting between 10 to 30 minutes.

Medical and Therapeutic Potential[edit | edit source]

Research into the medical and therapeutic potential of Salvinorin A is still in its early stages. Preliminary studies have suggested that the compound may have potential applications in the treatment of various psychiatric disorders, including depression, anxiety, and addiction. However, further research is needed to fully understand the mechanisms of action and potential therapeutic benefits of Salvinorin A.

Legal Status[edit | edit source]

The legal status of Salvinorin A varies across different countries and jurisdictions. In some countries, such as the United States, Salvinorin A is classified as a Schedule I controlled substance, making it illegal to possess, distribute, or manufacture. In other countries, such as the Netherlands, Salvinorin A is not specifically regulated, but its sale and distribution may be subject to certain restrictions.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD