Scavenger receptor (endocrinology)

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Scavenger receptor is a group of proteins that are involved in the process of endocrinology. They are primarily known for their role in the immune system, where they help to remove harmful substances from the body. However, they also play a crucial role in the endocrine system, where they are involved in the regulation of hormone levels and the response to stress.

Function[edit | edit source]

Scavenger receptors are a diverse group of proteins that are found on the surface of many different types of cells. They are named for their ability to "scavenge" or remove harmful substances from the body, including damaged cells, bacteria, and other foreign substances. In the endocrine system, scavenger receptors are involved in the regulation of hormone levels and the response to stress. They do this by binding to and removing hormones and other signaling molecules from the bloodstream, which helps to maintain the balance of these substances in the body.

Types[edit | edit source]

There are several different types of scavenger receptors, each with its own specific function. These include:

  • Scavenger receptor class A (SR-A): This type of receptor is found on the surface of macrophages, a type of white blood cell that is involved in the immune response. SR-A receptors bind to and remove a variety of harmful substances, including bacteria and damaged cells.
  • Scavenger receptor class B (SR-B): SR-B receptors are found on the surface of many different types of cells, including cells in the liver, adrenal glands, and the endocrine system. They are involved in the regulation of cholesterol levels in the body, as well as the response to stress.
  • Scavenger receptor class C (SR-C): SR-C receptors are less well understood than SR-A and SR-B receptors. However, they are thought to be involved in the immune response, as well as the regulation of hormone levels.

Role in Disease[edit | edit source]

Scavenger receptors play a crucial role in the body's defense against disease. However, when they are not functioning properly, they can contribute to the development of a variety of diseases, including atherosclerosis, diabetes, and certain types of cancer.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD