Serosa

Serosa is a smooth tissue membrane consisting of two layers of mesothelium, which secrete serous fluid. The inner layer that covers organs (viscera) in body cavities is called the visceral membrane. A second layer of epithelial cells of the serosa, called the parietal layer, lines the body wall.

Structure

Serosa is made up of simple squamous epithelium (mesothelium) and a thin layer of loose connective tissue. This structure secretes a serous fluid that fills the space between the visceral and parietal layers, providing lubrication to reduce friction from muscle movement.

Function

The main function of the serosa is to reduce friction between adjacent organs. It also serves as a barrier to prevent the spread of infections from one organ to another within a body cavity.

Clinical significance

Inflammation of the serosa, known as serositis, can occur in various diseases, including systemic lupus erythematosus, rheumatoid arthritis, and pericarditis. This can lead to the formation of adhesions between the organs and the body wall, which can cause chronic pain and organ dysfunction.

See also

• Mesothelium
• Peritoneum
• Pleura
• Pericardium

References

Serosa Resources
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