Small cleaved cell

Small Cleaved Cell

A Small Cleaved Cell is a type of lymphocyte, a subtype of white blood cell, that has undergone a process known as cleavage. This process results in the cell having a distinct appearance, with a smaller size and a cleaved or notched nucleus. Small cleaved cells are often associated with certain types of lymphoma, including Follicular Lymphoma and Mantle Cell Lymphoma.

Characteristics

Small cleaved cells are characterized by their small size and the presence of a cleaved or notched nucleus. The cleavage is a result of the cell undergoing a process known as mitosis, where the cell divides to produce two daughter cells. During this process, the nucleus of the cell is also divided, resulting in the characteristic cleaved appearance.

Association with Lymphomas

Small cleaved cells are often associated with certain types of lymphomas. In particular, they are commonly found in Follicular Lymphoma, a type of non-Hodgkin lymphoma that affects the B cells of the immune system. These cells are also associated with Mantle Cell Lymphoma, another type of non-Hodgkin lymphoma that also affects the B cells.

Diagnosis and Treatment

The presence of small cleaved cells can be identified through a biopsy and subsequent microscopic examination of the tissue. The cells can be stained with specific antibodies to identify the presence of certain proteins, which can help to confirm the diagnosis.

Treatment for lymphomas associated with small cleaved cells typically involves chemotherapy, radiation therapy, and in some cases, stem cell transplantation. The choice of treatment depends on the specific type of lymphoma, the stage of the disease, and the patient's overall health.

See Also

• Lymphocyte
• Lymphoma
• Follicular Lymphoma
• Mantle Cell Lymphoma