Sofosbuvir/daclatasvir

From WikiMD's Food, Medicine & Wellness Encyclopedia

Sofosbuvir/daclatasvir is a medication combination used for the treatment of hepatitis C. It is a combination of two antiviral medications, sofosbuvir and daclatasvir.

Etymology[edit | edit source]

The name "sofosbuvir" is derived from the chemical structure of the drug, which is a type of nucleotide analog. The "sofo" part of the name comes from the chemical name "Sofosbuvir", while the "buvir" part is a common suffix for antiviral medications. The name "daclatasvir" is also derived from the chemical structure of the drug, with "dacla" coming from the chemical name "Daclatasvir" and "tasvir" being a common suffix for antiviral medications.

Usage[edit | edit source]

Sofosbuvir/daclatasvir is used to treat chronic hepatitis C infection. It is used in combination with other antiviral medications to reduce the amount of hepatitis C virus in the body, helping the body's immune system fight the infection.

Mechanism of Action[edit | edit source]

Sofosbuvir works by inhibiting the hepatitis C virus (HCV) NS5B protein, which is essential for the replication of the HCV. Daclatasvir works by inhibiting the HCV NS5A protein, which is also essential for the replication of the HCV.

Side Effects[edit | edit source]

Common side effects of sofosbuvir/daclatasvir include fatigue, headache, nausea, and difficulty sleeping. Serious side effects may include a slow heart rate and reactivation of hepatitis B.

Related Terms[edit | edit source]

Sofosbuvir/daclatasvir Resources
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Contributors: Prab R. Tumpati, MD