Solitary lymphatic nodule
Solitary lymphatic nodule (also known as isolated lymphatic nodule or solitary lymphoid follicle) is a small, localized collection of lymphoid tissue usually found in the mucosa of the gastrointestinal tract and respiratory tract.
Structure[edit | edit source]
Solitary lymphatic nodules are spherical or oval in shape and are composed of lymphocytes, a type of white blood cell that plays a crucial role in the immune system. They are surrounded by a capsule of connective tissue and are typically less than 1 cm in diameter.
Function[edit | edit source]
The primary function of solitary lymphatic nodules is to participate in the immune response. They contain B cells, T cells, and dendritic cells, all of which are involved in the recognition and response to foreign antigens. When an antigen is detected, these cells initiate an immune response, which can include the production of antibodies by B cells.
Clinical significance[edit | edit source]
Solitary lymphatic nodules can become enlarged or inflamed in response to infection or disease, a condition known as lymphadenopathy. They can also be involved in certain diseases, such as Crohn's disease and ulcerative colitis, which are characterized by chronic inflammation of the gastrointestinal tract. In rare cases, solitary lymphatic nodules can become malignant, leading to a type of cancer known as lymphoma.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD