Suzetrigine

Suzetrigine

Suzetrigine is a pharmacological agent that is classified as a calcium channel blocker. It is primarily used in the treatment of bipolar disorder and epilepsy.

Pharmacology

Suzetrigine works by inhibiting the influx of calcium ions into cells, which in turn reduces the excitability of neurons. This mechanism of action is similar to other calcium channel blockers, but Suzetrigine has a unique chemical structure that allows it to have a longer duration of action and a wider therapeutic window.

Clinical Use

Suzetrigine is primarily used in the treatment of bipolar disorder and epilepsy. In bipolar disorder, it is used as a mood stabilizer to prevent manic episodes. In epilepsy, it is used to reduce the frequency and severity of seizures.

Side Effects

Like all medications, Suzetrigine can cause side effects. The most common side effects include dizziness, fatigue, and gastrointestinal disturbances. In rare cases, it can cause serious side effects such as cardiac arrhythmias and liver damage.

History

Suzetrigine was first synthesized in the 1980s by a team of researchers at the University of Tokyo. It was later developed into a medication by the pharmaceutical company Eisai Co., Ltd., and it was approved for use in Japan in 1995.

See Also

• Calcium channel blocker
• Bipolar disorder
• Epilepsy

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