TDI-11861

Chemical compound

{{Drugbox | verifiedfields = changed | verifiedrevid = 477002123 | IUPAC_name = (2S)-2-[[4-[[4-(4-fluorophenyl)-1,3-thiazol-2-yl]amino]pyrimidin-2-yl]amino]-N-methyl-3-phenylpropanamide | image = TDI-11861_structure.png | image2 = }}

TDI-11861 is a chemical compound that has been investigated for its potential therapeutic applications, particularly in the treatment of cancer. It is a small molecule inhibitor that targets specific protein kinases involved in the regulation of cell growth and proliferation.

Chemical Structure

Chemical structure of TDI-11861

TDI-11861 is characterized by its complex chemical structure, which includes a thiazole ring, a pyrimidine moiety, and a phenylpropanamide group. The presence of a fluorophenyl group contributes to its binding affinity and specificity for its target kinases.

Mechanism of Action

TDI-11861 functions as a kinase inhibitor, specifically targeting enzymes that play a critical role in the signaling pathways that regulate cell division and survival. By inhibiting these kinases, TDI-11861 can disrupt the signaling processes that lead to uncontrolled cell proliferation, a hallmark of cancer.

Therapeutic Potential

The primary focus of research on TDI-11861 has been its application in oncology. Preclinical studies have shown that TDI-11861 can effectively inhibit the growth of various cancer cell lines in vitro. Its ability to target multiple kinases makes it a promising candidate for the treatment of cancers that are driven by aberrant kinase activity.

Pharmacokinetics

The pharmacokinetic profile of TDI-11861 is an important consideration in its development as a therapeutic agent. Studies have investigated its absorption, distribution, metabolism, and excretion (ADME) properties to optimize its efficacy and minimize potential side effects.

Development and Research

TDI-11861 is still under investigation, with ongoing research aimed at understanding its full therapeutic potential and safety profile. Clinical trials are necessary to determine its efficacy in humans and to identify any adverse effects that may arise during treatment.

Related Pages

• Protein kinase inhibitor
• Cancer treatment
• Signal transduction