Tenascin X
Tenascin-X is a large extracellular matrix glycoprotein that plays a crucial role in the structural integrity of connective tissues. It is encoded by the TNXB gene located on chromosome 6 in humans.
Function[edit | edit source]
Tenascin-X is involved in the organization and maintenance of the extracellular matrix, which provides structural support to tissues and influences cell behavior. It is particularly important in the skin, muscles, and blood vessels.
Clinical significance[edit | edit source]
Mutations in the TNXB gene can lead to a condition known as Ehlers-Danlos syndrome type tenascin-X deficient, which is characterized by hyperelastic skin, joint hypermobility, and tissue fragility. This condition highlights the importance of tenascin-X in maintaining tissue integrity.
Interactions[edit | edit source]
Tenascin-X interacts with other extracellular matrix proteins and cell surface receptors, influencing cell adhesion, migration, and proliferation. These interactions are critical for tissue repair and development.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
