Tetroxoprim

Tetroxoprim is a synthetic antibiotic used in the treatment of various bacterial infections. It belongs to the class of sulfonamides, which are known for their broad-spectrum antibacterial activity. Tetroxoprim works by inhibiting the production of folic acid in bacteria, which is essential for their growth and reproduction.

Mechanism of Action

Tetroxoprim inhibits the enzyme dihydrofolate reductase (DHFR), which is involved in the synthesis of folic acid in bacteria. By blocking this enzyme, the drug prevents the bacteria from producing folic acid, thereby inhibiting their growth and reproduction.

Uses

Tetroxoprim is used to treat a variety of bacterial infections, including urinary tract infections, respiratory tract infections, and skin infections. It is also used in combination with other antibiotics to treat certain types of pneumonia and meningitis.

Side Effects

Like all antibiotics, Tetroxoprim can cause side effects. These may include nausea, vomiting, diarrhea, and skin rash. In rare cases, it can cause serious side effects such as anemia, liver damage, and kidney damage.

Precautions

Patients with a history of allergy to sulfonamides should not take Tetroxoprim. It should also be used with caution in patients with kidney disease or liver disease, as these conditions can affect the body's ability to metabolize and eliminate the drug.

Interactions

Tetroxoprim can interact with other medications, including anticoagulants, antidiabetic drugs, and certain anticonvulsants. These interactions can affect the effectiveness of the medications and increase the risk of side effects.

See Also

• Sulfonamides
• Antibiotics
• Bacterial Infections