Theileriidae
Theileriidae[edit | edit source]
Theileriidae is a family of parasitic protozoa that belong to the phylum Apicomplexa. They are commonly found in ruminants, particularly cattle, and are known to cause diseases such as tropical theileriosis and East Coast fever. The family is named after Arnold Theiler, a South African veterinarian who made significant contributions to the study of tick-borne diseases.
Taxonomy[edit | edit source]
Theileriidae is classified under the order Piroplasmida, which is a group of parasitic protozoa that infect the red blood cells of vertebrates. Within the family Theileriidae, there are several genera, including Theileria, Cytauxzoon, and Babesia. Each genus consists of multiple species that have specific host preferences and geographical distributions.
Morphology[edit | edit source]
Members of the family Theileriidae are characterized by their small size and unique morphology. They have a complex life cycle that involves both vertebrate and invertebrate hosts. In the vertebrate host, the parasites invade the red blood cells and undergo asexual reproduction, leading to the destruction of the host's red blood cells. In the invertebrate host, which is usually a tick, the parasites undergo sexual reproduction and produce specialized forms called sporozoites, which are then transmitted to the vertebrate host during tick feeding.
Pathogenesis[edit | edit source]
Theileriidae parasites are responsible for causing various diseases in ruminants. Tropical theileriosis, caused by species of the genus Theileria, is prevalent in tropical and subtropical regions and can result in significant economic losses in the livestock industry. East Coast fever, caused by Theileria parva, is a major concern in eastern and southern Africa, where it affects cattle populations and hinders agricultural development.
Diagnosis and Treatment[edit | edit source]
Diagnosing Theileriidae infections in animals can be challenging due to the similarity of symptoms with other diseases. However, various diagnostic techniques, such as microscopic examination of blood smears, serological tests, and molecular methods, can be employed to identify the presence of the parasites. Treatment options for Theileriidae infections include the use of antiprotozoal drugs, such as imidocarb dipropionate and buparvaquone, which can help control the disease and reduce the severity of symptoms.
Prevention and Control[edit | edit source]
Preventing and controlling Theileriidae infections primarily involve implementing effective tick control measures. This can be achieved through the use of acaricides, which are chemicals that kill or repel ticks, and the implementation of proper pasture management practices. Additionally, the development of vaccines against specific Theileria species has shown promising results in reducing the impact of the diseases caused by these parasites.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD