Toker cell
Toker cells are a type of epithelial cell found in the human body. They were first described by Claudio D. Toker in 1970. Toker cells are typically found in the nipple and areola regions of the human breast. They are considered to be precursors of Paget's disease of the breast, a rare type of cancer that outwardly may have the appearance of eczema, with skin changes involving the nipple of the breast.
Characteristics[edit | edit source]
Toker cells are clear cells, meaning they have a clear cytoplasm when viewed under a microscope. They are typically larger than the surrounding keratinocytes and are found in the epidermis, the outermost layer of the skin. Toker cells have a round shape and a large, round nucleus. They are often found in clusters.
Clinical significance[edit | edit source]
Toker cells are considered to be precursors to Paget's disease of the breast. This disease is a rare type of breast cancer that begins in the milk ducts and spreads to the skin of the nipple and areola. The presence of Toker cells can be an early indicator of this disease.
Research[edit | edit source]
Research into Toker cells is ongoing. Studies have suggested that these cells may also be present in other areas of the body, such as the vulva. Further research is needed to fully understand the role of Toker cells in the development of cancer.
See also[edit | edit source]
References[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD