Toltrazuril

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Toltrazuril is a medication used in veterinary medicine to treat coccidiosis, a parasitic disease affecting a variety of animals. It is a triazinone derivative and is marketed under various trade names, including Baycox by Bayer.

Etymology[edit | edit source]

The term "Toltrazuril" is derived from its chemical structure, which includes a toluidine group and a triazinone ring. The suffix "-zuril" is common in the names of anti-coccidial drugs.

Usage[edit | edit source]

Toltrazuril is used to treat coccidiosis in poultry, pigs, cattle, sheep, and goats. It is also used in horses, dogs, and cats. The drug is administered orally, usually in the form of a suspension. It is effective against all intracellular development stages of Coccidia, a group of parasitic protozoans.

Mechanism of Action[edit | edit source]

Toltrazuril works by damaging the intracellular developmental stages of coccidia, without damaging the host cells. It interferes with the division of the protozoan cells and the activity of certain enzymes, leading to the death of the parasites.

Side Effects[edit | edit source]

Side effects of Toltrazuril are rare but can include diarrhea, vomiting, and loss of appetite. In horses, it can cause mild colic and loose stools.

Related Terms[edit | edit source]

  • Coccidiosis: A parasitic disease caused by Coccidia.
  • Bayer: A German multinational pharmaceutical company that markets Toltrazuril under the trade name Baycox.
  • Coccidia: A group of parasitic protozoans that cause coccidiosis.
Toltrazuril Resources
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Contributors: Prab R. Tumpati, MD