Tomographic reconstruction
Therapeutic angiogenesis is a form of treatment that uses the body's natural ability to grow new blood vessels to improve blood flow to areas of the body that are not receiving enough blood due to blocked or damaged blood vessels. This treatment is often used for conditions such as coronary artery disease and peripheral artery disease.
Mechanism of Action[edit | edit source]
Therapeutic angiogenesis works by stimulating the growth of new blood vessels from existing ones, a process known as angiogenesis. This is achieved through the introduction of growth factors, such as vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF), into the affected area. These growth factors bind to receptors on the surface of endothelial cells, triggering a series of events that lead to the formation of new blood vessels.
Clinical Applications[edit | edit source]
Therapeutic angiogenesis has been studied for use in a variety of medical conditions, including:
- Coronary artery disease: In patients with coronary artery disease, therapeutic angiogenesis can help improve blood flow to the heart muscle, reducing symptoms such as chest pain and shortness of breath.
- Peripheral artery disease: For patients with peripheral artery disease, therapeutic angiogenesis can help improve blood flow to the legs, reducing pain and improving mobility.
- Diabetic foot ulcers: Therapeutic angiogenesis can help improve healing in patients with diabetic foot ulcers by increasing blood flow to the affected area.
Risks and Challenges[edit | edit source]
While therapeutic angiogenesis holds promise, there are several challenges and risks associated with this treatment. These include the potential for uncontrolled growth of blood vessels, which could lead to complications such as bleeding or the growth of tumors. Additionally, the delivery of growth factors to the affected area can be challenging, and the effects of the treatment may not be long-lasting.
Future Directions[edit | edit source]
Research is ongoing to improve the effectiveness and safety of therapeutic angiogenesis. This includes the development of new delivery methods for growth factors, as well as the identification of new targets for therapy.
| Tomographic reconstruction Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
