Tropacocaine
Tropacocaine is a tropane alkaloid that is found naturally in the coca plant. It is a local anesthetic that is structurally similar to cocaine. Tropacocaine was first isolated from the coca plant in 1891.
History[edit | edit source]
Tropacocaine was first isolated from the coca plant in 1891 by the German chemist Richard Willstätter. Willstätter was studying the chemical composition of the coca plant and discovered that tropacocaine was one of the plant's primary alkaloids.
Chemistry[edit | edit source]
Tropacocaine is a tropane alkaloid, which means it is a naturally occurring chemical compound that contains a tropane ring structure. This structure is composed of a seven-membered ring with a nitrogen atom and two additional carbon atoms. Tropacocaine is structurally similar to cocaine, but it has a different arrangement of atoms within the tropane ring.
Pharmacology[edit | edit source]
Tropacocaine acts as a local anesthetic by blocking sodium channels in nerve cells, which prevents the transmission of nerve impulses. This results in a loss of sensation in the area where the drug is applied. Tropacocaine is less potent than cocaine as a local anesthetic, but it has a shorter duration of action.
Medical Use[edit | edit source]
Tropacocaine is used in medical settings as a local anesthetic, particularly in ophthalmology. It is applied topically to numb the surface of the eye before procedures such as cataract surgery.
Legal Status[edit | edit source]
In many countries, including the United States, tropacocaine is a controlled substance due to its structural similarity to cocaine. It is classified as a Schedule II controlled substance under the Controlled Substances Act in the United States.
See Also[edit | edit source]
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