Tropicamide/hydroxyamfetamine

Tropicamide/hydroxyamfetamine is a combination of two drugs, Tropicamide and Hydroxyamfetamine, used in the field of ophthalmology for diagnostic purposes.

Overview[edit | edit source]

Tropicamide is a muscarinic antagonist used to dilate the pupil and relax the ciliary muscle in the eye, a process known as mydriasis. Hydroxyamfetamine, on the other hand, is a sympathomimetic amine that stimulates the release of norepinephrine from nerve endings, leading to pupil dilation.

The combination of tropicamide and hydroxyamfetamine is primarily used to dilate the pupil for eye examinations. It can also be used to diagnose Horner's syndrome, a condition that affects the nervous system and results in decreased pupil size and drooping of the eyelid on one side of the face.

Side Effects[edit | edit source]

Possible side effects of tropicamide/hydroxyamfetamine include blurred vision, eye irritation, increased intraocular pressure, and allergic reactions. In rare cases, systemic effects such as tachycardia, hypertension, palpitations, and psychotic reactions may occur.

Contraindications[edit | edit source]

Tropicamide/hydroxyamfetamine should not be used in patients with narrow-angle glaucoma, as it can increase intraocular pressure and worsen the condition. It should also be used with caution in patients with cardiovascular disease or hyperthyroidism due to the potential for increased heart rate and blood pressure.

Interactions[edit | edit source]

Tropicamide/hydroxyamfetamine may interact with other medications, including antihistamines, antipsychotics, antidepressants, and antiparkinsonian drugs, which can increase the risk of side effects.

See Also[edit | edit source]

Tropicamide/hydroxyamfetamine Resources
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