Tufted cell
Tufted Cell
A tufted cell is a type of neuron found in the olfactory system, specifically in the olfactory bulb. These cells are named for their distinctive tuft of dendrites, which extend from the cell body and form synapses with the olfactory receptor neurons.
Structure[edit | edit source]
Tufted cells are characterized by a single, thick axon that extends from the cell body into the deeper layers of the olfactory bulb. The dendrites of these cells form a tuft, or cluster, at the surface of the bulb, where they receive input from the olfactory receptor neurons. The dendrites of tufted cells are shorter and less branched than those of mitral cells, another type of neuron in the olfactory bulb.
Function[edit | edit source]
Tufted cells play a crucial role in the processing of olfactory information. They receive input from the olfactory receptor neurons and transmit this information to other neurons in the olfactory bulb and the olfactory cortex. Tufted cells are thought to be involved in the initial stages of odor discrimination and identification.
Clinical significance[edit | edit source]
Abnormalities in the structure or function of tufted cells can lead to disorders of the olfactory system, such as anosmia (loss of smell) or hyposmia (reduced ability to smell). Research is ongoing to better understand the role of tufted cells in these and other olfactory disorders.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD