Tumor-infiltrating lymphocyte
(TOO-mer-IN-fil-TRAY-ting LIM-foh-site) A type of immune cell that has moved from the blood into a tumor to try and attack the cancer. In cancer therapy, tumor-infiltrating lymphocytes are removed from a patient’s tumor and are then treated in the laboratory with substances that activate the lymphocytes to help them better kill the patient’s cancer cells. Large numbers of these activated lymphocytes are then given back to the patient to help the immune system fight cancer. Also called TIL.
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Contributors: Prab R. Tumpati, MD